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the mammalian immune system, teleost erythrocytes, neutrophils and granulocytes are believed to reside in the spleen whereas lymphocytes are the major cell type found in the thymus.[35][36] In xxxx, a lymphatic system similar to that in mammals was described in one species of teleost fish, the zebrafish. Although not conf irmed as yet, this system presumably will be where naive (unstimulated) T cells accumulate while waiting to encounter an antigen.[3 Like other animals, fish suffer from diseases and parasites. To prevent disease they have a variety of defenses. Non-specific defenses include the skin and scales, as well as the mucus layer secreted by the epidermis that traps and inhibits the growth of microorganisms. If pathogens breach these defenses, fish can develop an inflammatory response that increases blood flow to the infected region and delivers white blood cells that attempt to destroy pathogens. Specific defenses respond to particular pathogens recognised by the fish's body, i.e., an immune response.[38] In recent years, vaccines have become widely used in aquaculture and also with fish, for example furunculosis vaccines in farmed salmon and koi herpes virus in koi.[39][40] The brain stem or myelencephalon is the brain's posterior.[17] As well as controlling some muscles and body organs, in bony fish at least, the brain stem governs respira Most fish possess highly developed sense organs. Nearly all daylight fish have color vision that is at least as good as a human's. Many fish also have chemoreceptors that